Posted by M. W. Myers, D.V.M. on March 26, 2003 at 22:10:34:
In Reply to: Re: Phemphigus foliaceus/canker posted by Jenni MacPhail on March 24, 2003 at 21:58:54:
: : I would not wait on radiographs.
: : How was the pemphigus diagnosed? If it is truly pemphigus there are several ways to attempt control of the condition. Note that "control" is the operative word. You can try 4Life Research products - Stress Pack followed with their Equine Performance and Show product. You may contact me directly for details. Secondly, corticosteroids may give some degree of control, but this may not be permanent and can have deleterious side efects. Aurothioglucose is another option for control, but may bit pricey in the horse.
: : Radiograph this horse now.
: : Other metabolic testing may be in order as well.
: : M. W. Myers, D.V.M.
: Dr. Myers,
: I appreciate your reply and will make arrangements for xrays asap. Diagnosis was: the vet took a history, examined the horse and told me what she believed it was. No biopsy or bloodwork was done. What is the normal prodedure? Is there a bloodtest (think I remember reading about that..)
: We opted not to use steroids at this time as the horse is sound and not in pain. Go figure.
: I have read about the 4Life products and am intrigued. How do they differ from Vita-Flex's GlutaSyn? What is aurothiglucose?
: Thanks,
: Jenni
This is not the way to diagnose pemphigus. The differentials for this horse include - severe laminitis with sinking (some sinkers are not painful as the circulation cuts off and the laminae dewgenerate), damaged and granulating laminae, Borreliosis (Lyme disease), ergot toxicosis, selenium toxicity, deep seated hoof infections. Only biopsy can diagnose pemphigus and this needs to be accurately diagnosed before you attempt to treat it.
Transfer factor has very little relation to glutathione. Glutathione is a T cell stimulator while transfer factor is a cytokine modulator.
Aurothioglucose is commonly referred to as "gold shots". They suppress certain portions of the immune response and are value in pemphigus therapy.
You do need an accurate diagnosis on this horse.
M. W. Myers, D.V.M.